Colin Sheppard is Senior Scientist in the Nanophysics Department at the Italian Institute of Technology, Genoa. He obtained his PhD degree from University of ambridge. Previously he was Professor in the Departments of Bioengineering, Biological Sciences and Diagnostic Radiology at NUS, Professor of Physics at the University of Sydney, and University Lecturer in Engineering Science at the University of Oxford. He has held visiting positions at many universities, including MIT, Stanford, UC-Berkeley, Tsinghua, Zhejiang, Tokyo, EPFL, TU-Delft, UNSW and Melbourne. He developed an early laser microscope (1975), patented scanning microscopy using Bessel beams (1977), gave the first demonstration of scanning two-photon microscopy (1977), proposed two-photon fluorescence and CARS microscopy (1978), launched the first commercial confocal microscope (1982), and developed the first confocal microscope with computer control and storage (1983). In 1988, he proposed scanning microscopy using a detector array with pixel reassignment, now known as image scanning microscopy.
Two of the most important modern diagnostic techniques for imaging the eye are the confocal laser ophthalmoscope, and optical coherence tomography. These are both versions of techniques developed for general microscopy. But investigation of the history of imaging techniques shows that many developments came from the area of ophthalmology. The history of some of these methods is presented, and some newer methods introduced, some of which may have potential applications in imaging of the eye.